The global next generation sequencing (NGS) sample preparation market size was valued at USD 2.76 billion in 2018 and is expected to grow at a CAGR of 11.19% during the forecast period. Development of companion diagnostics and personalized medicine is expected to enhance the adoption of next-generation sequencing protocols in clinical practice. NGS technology is widely applicable in theranostics domain thus leading to growth in NGS sample preparation market.
In addition, an increase in sequencing capacity and speed has led to a rise in demand for high-throughput NGS sample handling solutions. Therefore, key players are focused on the development of automated platforms for sample preparation for next-generation sequencing.
For instance, the Bravo NGS manufactured by Agilent Technologies, Inc. efficiently automates library preparation for NGS implementation and reduces the overall time of the process. A laboratory technician can use Bravo NGS to prepare whole genome libraries for nearly 1,000 samples every week. The system also reduces variability by nearly 39% as compared to other manual methods.
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Further Key Findings from the Report Suggest:
Semi-automated library preparation segment dominated the workflow segment in 2018 and is projected to remain on the top in terms of revenue generation in the coming years
Combination of automated and manual approaches for library preparation is attributed to the highest share of the segment
Market entities are engaged in strategic partnerships to develop library preparation protocols on semi-automated technologies
For instance, Illumina partnered with Hamilton Company for developing automated and semi-automated library preparation platform. The automation of preliminary steps aid in the reduction of sample handling time
Oncology was the largest and consumer genomics was the fastest-growing application segment from 2018 to 2025
Introduction of targeted gene panels for cancerous cells is expected to drive demand for efficient sample handling solutions in the coming years
Illumina is constantly working towards the development of next-generation sequencing based in vitro diagnostic (IVD) solutions for cancer diagnostics.
The company has partnered with some of the leading biotechnology firms to develop companion diagnostics targeting cancer
For instance, Illumina partnered with Loxo Oncology in April 2018 to develop NGS-based pan-cancer companion diagnostic solutions for solid tumors
Similarly, continuous introduction of novel solutions for consumer genomics is driving growth in the NGS sample preparation market
Companies such as 23andMe, Color Genomics, Helix, and Counsyl are active players in the consumer genomics segment
Clinical research segment is projected to grow with the highest CAGR in the coming years
Rising adoption of sequencing associated CLIA waived diagnostic tests among these end-users is anticipated to boost growth
Although U.S. accounted for the largest share on the current market scenario, potential opportunities offered by emerging nations is attributive to the fastest growth rate of Asia Pacific region
China and India are expected to witness substantial penetration in the coming years with respect to implementation of biotechnological advances
Agilent Technologies.; BGI; Biomatters Ltd.; Bio-Rad Laboratories, Inc.; Congenica Ltd; DNASTAR; Eurofins Scientific; F. Hoffmann-La Roche Ltd; Foundation Medicine; Genomatix GmbH; Illumina; Macrogen; Myriad Genetics; Oxford Nanopore Technologies; Pacific Biosciences of California; Partek Incorporated; Perkin Elmer; PierianDx; QIAGEN; Quest Diagnostics Incorporated; and Thermo Fisher Scientific are the prominent participants operating in this market
These companies are working towards the development of novel products and workflows that can help ease the bottlenecks associated with the integration of sequencing in clinical medicine
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Application Insights
Oncology segment accounted for the largest share in 2018 owing to the presence of several players engaged in the development of oncology targeted panels. These panels pronounce the demand for sample preparation solutions. Companies are partnering with the leading biotechnology firms for the development of oncology companion diagnostics products.
For instance, in April 2018 Illumina collaborated with Bristol-Myers Squibb to manufacture and market companion diagnostics assays for the latter’s oncology immunotherapies. Illumina also partnered with Loxo Oncology in April 2018 for the development of NGS-based pan-cancer companion diagnostic solutions for solid tumors.
Similarly, other market players are also striving to enhance their product offerings for oncology companion diagnostics. In this regard, Biodesix, Inc. signed an agreement with Thermo Fisher Scientific in July 2019 to develop an NGS assay for Non-small Cell Lung Cancer (NSCLC). The company also seeks to get FDA-Premarket approval (PMA) classification for the test.
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Grand View Research has segmented the NGS sample preparation market on the basis of workflow, application, end use, and region:
NGS Sample Preparation Workflow Outlook (Revenue, USD Million, 2014 – 2025)
NGS Library Preparation Kits
Semi-automated Library Preparation
Automated Library Preparation
Clonal Amplification
NGS Sample Preparation Application Outlook (Revenue, USD Million, 2014 – 2025)
Oncology
Clinical Investigation
Reproductive Health
HLA Typing/Immune System Monitoring
Metagenomics, Epidemiology & Drug Development
Agrigenomics & Forensics
Consumer Genomics
NGS Sample Preparation End-Use Outlook (Revenue, USD Million, 2014 – 2025)
Academic Research
Clinical Research
Hospitals & Clinics
Pharma & Biotech Entities
Other Users
NGS Sample Preparation Regional Outlook (Revenue, USD Million, 2014 – 2025)
North America
U.S.
Canada
Europe
Germany
UK
Asia Pacific
Japan
China
Latin America
Brazil
MEA
South Africa
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